Benjamin Djulbegovic is a Professor of Medicine at the Medical University of South Carolina, Charleston, where he serves as a section Chief of Benign Hematology and Director of the Hematology Stewardship Program. His primary academic and research interest lies in attempts to measure and optimize clinical research and practice of medicine by understanding the nature of medical evidence and decision-making. To this effect, his work aims to close the translational research circle by integrating methods and techniques across evidence-based medicine (EBM), predictive analytics, health outcome research, and decision sciences with the goals of reducing overuse, underuse, and misuse of delivery of health services to improve patients' health outcomes.

Dr. Djulbegovic has systematically applied the science of EBM and decision analysis to the entire fields of hematology and oncology that, resulted in two books; the book on "Reasoning and decision-making in hematology" was listed as one of the best books by J Natl Cancer Inst and the book "Decision Making in Oncology. Evidence-based management" was assessed as "one of the first and best attempts to apply an evidence-based approach to the practice of medical oncology."

As of April 2022, he has published over 400 papers in peer-review journals, 196 abstracts, and numerous book chapters. He also received numerous awards for his work, published in major scientific and medical journals, including Nature, Lancet, JAMA, New England Journal of Medicine, Annals of Internal Medicine, BMJ, etc. He has also widely taught these subjects. During the last 25 years, Dr. Djulbegovic has received continuous external funding from federal and private entities. He was also selected in Newsweek's list of Top Cancer Doctors and, since 2011 continuously been selected among 1% of top US doctors by the US News & World Report in the field of hematology. His current h-index is 72, and he has been regularly included in the top 1% cited scientists worldwide.